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Science. 2012 Oct 5;338(6103):79-82. doi: 10.1126/science.1222942.

The science of resilience: implications for the prevention and treatment of depression.

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Yale University School of Medicine and Yale Child Study Center, U.S. Department of Veterans Affairs National Center for Post-Traumatic Stress Disorder, VA Connecticut Healthcare System, West Haven, CT 06516, USA.


Human responses to stress and trauma vary widely. Some people develop trauma-related psychological disorders, such as posttraumatic stress disorder (PTSD) and depression; others develop mild to moderate psychological symptoms that resolve rapidly; still others report no new psychological symptoms in response to traumatic stress. Individual variability in how animals and humans respond to stress and trauma depends on numerous genetic, developmental, cognitive, psychological, and neurobiological risk and protective factors.

[Indexed for MEDLINE]

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