Palladium-catalyzed dehydrogenation/oxidative cross-coupling sequence of β-heteroatom-substituted ketones

Youngtaek Moon; Daeil Kwon; Sungwoo Hong

doi:10.1002/anie.201206610

Palladium-catalyzed dehydrogenation/oxidative cross-coupling sequence of β-heteroatom-substituted ketones

Angew Chem Int Ed Engl. 2012 Nov 5;51(45):11333-6. doi: 10.1002/anie.201206610. Epub 2012 Oct 4.

Authors

Youngtaek Moon¹, Daeil Kwon, Sungwoo Hong

Affiliation

¹ Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon, Korea.

PMID: 23038616
DOI: 10.1002/anie.201206610

Abstract

Concise and selective: the title one-pot sequence allows formation of the enone functionality and subsequent cross-coupling. The process provides access to highly functionalized cyclic enolones and enaminones from readily accessible β-heteroatom-substituted cyclic ketones.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Chromones / chemistry
Hydrogenation
Ketones / chemistry*
Molecular Structure
Oxidative Coupling
Palladium / chemistry*
Quinolones / chemistry

Substances

Chromones
Ketones
Quinolones
Palladium