Format

Send to

Choose Destination
See comment in PubMed Commons below
Org Lett. 2012 Oct 19;14(20):5169-71. doi: 10.1021/ol302172y. Epub 2012 Oct 3.

Trimethylaluminum-triflimide complexes for the catalysis of highly hindered Diels-Alder reactions.

Author information

1
Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA. jung@chem.ucla.edu

Abstract

Two catalysts, Me(2)AlNTf(2) and MeAl(NTf(2))(2), derived from the mixing of trimethylaluminum with triflimide, proved to be highly effective catalysts in hindered Diels-Alder reactions, generating the desired Diels-Alder cycloadducts from both hindered 2-silyloxydienes and hindered dienophiles. Thus reaction of 1 with 2 afforded the hindered cycloadduct 4 in excellent yield in 0.5-1.5 h at -40 °C.

PMID:
23030499
DOI:
10.1021/ol302172y
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Support Center