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Dermatol Clin. 1990 Jan;8(1):107-9.

Sensitization to povidone-iodine.

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Department of Occupational Dermatology, Free University Academic Hospital, Amsterdam, The Netherlands.


Eight patients are described with adverse skin reactions to povidone-iodine-containing preparations (Betadine). Patch test reactions were positive to povidone-iodine 5 or 10 per cent in petrolatum or to Betadine Solution, Ointment, or Scrub. In five of eight patients, also tested with potassium iodide in concentrations ranging from 5 to 20 per cent in petrolatum, the reactions were negative. Open tests with iodine tincture performed in three patients were completely negative. Allergy to povidone-iodine seems not to be based on sensitization to iodine.

[Indexed for MEDLINE]

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