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Comput Methods Programs Biomed. 2013 Jan;109(1):77-85. doi: 10.1016/j.cmpb.2012.08.009. Epub 2012 Sep 29.

Facilitating pharmacometric workflow with the metrumrg package for R.

Author information

1
Metrum Institute, Tariffville, CT, USA. timb@metrumrg.com

Abstract

metrumrg is an R package that facilitates workflow for the discipline of pharmacometrics. Support is provided for data preparation, modeling, simulation, diagnostics, and reporting. Existing tools and techniques are emphasized where available; original solutions are provided for otherwise unmet needs. In particular, metrumrg implements an R interface for the NONMEM(®) modeling software, optionally run in a distributed computing environment. The paradigm allows start-to-finish analyses in a single scripting language. Emphasis on text-based formats promotes traceability of results.

PMID:
23026560
DOI:
10.1016/j.cmpb.2012.08.009
[Indexed for MEDLINE]

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