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Indian Pediatr. 2012 Sep;49(9):750-2.

Leflunomide in systemic onset Juvenile idiopathic arthritis.

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1
Department of Paediatrics, Post Graduate Institute of Medical Education and Research, Dr Ram Manohar Lohia hospital, New Delhi, India.

Abstract

Methotrexate, the mainstay of treatment in Juvenile idiopathic arthritis, might not be effective in a few patients of polyarticular and systemic onset juvenile idiopathic arthritis. Use of biologicals like TNF-a blockers, the next line of preferred drugs is constrained by the high cost. We successfully used leflunomide in four patients.

PMID:
23024081
[Indexed for MEDLINE]
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