Format

Send to

Choose Destination
See comment in PubMed Commons below
Clin J Oncol Nurs. 2012 Oct;16(5):507-13.

Veno-occlusive disease in hematopoietic stem cell transplantation recipients.

Author information

  • 1Florida Hospital in Orlando, USA. elisabeth.c.sosa@gmail.com

Abstract

Veno-occlusive disease (VOD) is a potentially fatal complication of hematopoietic stem cell transplantation that affects the liver, as well as other organs. Although mild cases resolve on their own, severe cases of VOD carry a high mortality rate. The diagnosis usually is clinically based, with nonspecific signs such as weight gain, ascites, hepatomegaly, right upper quadrant abdominal pain, and elevated serum bilirubin. Although studies are ongoing, no U.S. Food and Drug Administration-approved treatments for VOD exist to date. Therefore, supportive care is a critical part of the treatment plan. Oncology nurses should be familiar with the risk factors and clinical signs of VOD so that patients can be monitored closely for its occurrence. Accurate and timely recognition of VOD is crucial for appropriate treatment.

PMID:
23022934
DOI:
10.1188/12.CJON.507-513
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Oncology Nursing Society
    Loading ...
    Support Center