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Infect Genet Evol. 2013 Jan;13:105-8. doi: 10.1016/j.meegid.2012.09.006. Epub 2012 Sep 26.

Microsatellite-based genotyping of Candida parapsilosis sensu stricto isolates reveals dominance and persistence of a particular epidemiological clone among neonatal intensive care unit patients.

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Department of Life Sciences Marcello Malpighi - Section of Microbiological, Genetic and Molecular Sciences - University of Messina, Viale F. Stagno d'Alcontres, 31 - 98166 Messina, Italy.


In this study, using multilocus microsatellite analysis, we report the genetic characterization of 27 Candida parapsilosis isolates recovered in two different periods of time (2007-2009 and 2011-2012) from infants hospitalized in the neonatal intensive care unit of a hospital in Messina, Italy. The results revealed the persistence and dominance of a particular infectious genotype among NICU patients and highlight the power of the used microsatellite markers in clarifying epidemiologic associations, detect micro-evolutionary variations and facilitating the recognition of outbreaks.

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