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Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Nov;114(5):610-5. doi: 10.1016/j.oooo.2012.05.011. Epub 2012 Sep 26.

Oral Candida colonization and candidiasis in patients with psoriasis.

Author information

1
Zarqa Governate Health Directorate, Ministry of Health, Jordan.

Abstract

OBJECTIVES:

The objective of this study was to investigate oral Candida colonization and candidosis in a group of patients with psoriasis and controls.

STUDY DESIGN:

A total of 100 patients with psoriasis and matched controls underwent the concentrated oral rinse test for Candida isolation. Candida species were identified by the VITEK 2 Identification System. Categorical variables were evaluated using the χ(2) test. The median Candida count was compared using the Mann-Whitney U test.

RESULTS:

Oral candidiasis was diagnosed in 3% of the patients with psoriasis. The Candida count and prevalence were significantly higher in the patients with psoriasis compared with controls (69% vs 44%, P < .001), but with no relationship to the severity or treatment of psoriasis. Oral Candida was significantly higher in late-onset (at age ≥30 years) compared with early-onset psoriasis (at age <30 years).

CONCLUSIONS:

Patients with psoriasis have increased oral Candida colonization and candidiasis. Further studies are needed to clarify the predisposing factor(s) for oral Candida in patients with psoriasis.

PMID:
23022022
DOI:
10.1016/j.oooo.2012.05.011
[Indexed for MEDLINE]

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