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Ann Transplant. 2012 Jul-Sep;17(3):133-7.

Guillain-Barré syndrome in the course of EBV infection after kidney transplantation--a case report.

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1
Department of Nephrology, Hypertension and Kidney Transplantation, Medical University of Łódź, Łódź, Poland.

Abstract

BACKGROUND:

Neurological complications are quite frequent in patients after solid organ transplantation, mostly affecting the central nervous system, and less frequently the peripheral nerves. Guillain-Barré syndrome (GBS), a reactive autoimmune disease of the nervous tissue, is the most common cause of acute polyneuropathy in adults following a viral or bacterial infection. GBS has been also linked to neurotoxic adverse effects of calcineurin inhibitors. This syndrome occurs relatively frequently in patients after bone marrow transplantation, but has been a rare complication in solid organ transplant recipients. Epstein-Barr virus (EBV) infection is relatively common in transplant recipients and in some cases may lead to neurological complications.

CASE REPORT:

In this report we present an interesting case of a patient who developed GBS in the course of EBV infection 1 year after kidney transplantation.

CONCLUSIONS:

In patients with rapid development of polyneuropathy after transplantation, Guillain-Barré syndrome should be excluded.

PMID:
23018266
[Indexed for MEDLINE]
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