Abstract
A 57-year-old man who had recently undergone a transrectal prostate biopsy for a rising prostate-specific antigen level developed postbiopsy necrotizing epididymo-orchitis (requiring orchiectomy) and then Gram-negative meningitis, despite fluoroquinolone administration for periprocedural prophylaxis and subsequent therapy. The causative organism proved to be a fluoroquinolone-resistant Escherichia coli strain from sequence type ST131.
Publication types
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Case Reports
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Anti-Bacterial Agents / administration & dosage
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Anti-Bacterial Agents / pharmacology
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Biopsy / adverse effects*
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Cluster Analysis
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Drug Resistance, Bacterial
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Electrophoresis, Gel, Pulsed-Field
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Epididymitis / complications*
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Epididymitis / microbiology
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Escherichia coli / drug effects
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Escherichia coli / genetics
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Escherichia coli / isolation & purification*
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Escherichia coli Infections / diagnosis*
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Fluoroquinolones / administration & dosage
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Fluoroquinolones / pharmacology
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Genotype
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Humans
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Male
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Meningitis, Bacterial / complications*
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Meningitis, Bacterial / microbiology
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Middle Aged
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Molecular Typing
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Orchitis / complications*
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Orchitis / microbiology
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Prostatic Neoplasms / diagnosis*
Substances
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Anti-Bacterial Agents
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Fluoroquinolones