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Chem Commun (Camb). 2012 Nov 11;48(87):10760-2. doi: 10.1039/c2cc35964b.

Intermolecular G-quadruplex-based universal quencher free molecular beacon.

Author information

1
State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, PR China.

Abstract

A simple and universal quencher-free molecular beacon (MB) with low background fluorescence is developed based on an intermolecular G-quadruplex signaling probe. Unlike previous fluorescent MB strategies, it can function without any fluorophore and quencher modifications on its hairpin sequence.

PMID:
23011465
DOI:
10.1039/c2cc35964b
[Indexed for MEDLINE]

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