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Tex Med. 1990 Jan;86(1):44-7.

Death following suspected alprazolam withdrawal seizures: a case report.

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Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston 77550.


This is a case report of severe psychosis and seizures following abrupt discontinuation of alprazolam and then the recurrence of seizures at the end of a gradual tapering schedule. The last of these seizures appeared to be a contributing factor in the patient's death. To the authors' knowledge, this is the first published report of a fatality associated with alprazolam withdrawal.

[Indexed for MEDLINE]

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