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Nat Rev Immunol. 2012 Oct;12(10):728-34. doi: 10.1038/nri3312.

The impact of probiotics and prebiotics on the immune system.

Author information

1
Department of Food, Bioprocessing & Nutrition Sciences, North Carolina State University, Raleigh, North Carolina 27695, USA. Klaenhammer@ncsu.edu

Abstract

Probiotics and prebiotics are increasingly being added to foodstuffs with claims of health benefits. Probiotics are live microorganisms that are thought to have beneficial effects on the host, whereas prebiotics are ingredients that stimulate the growth and/or function of beneficial intestinal microorganisms. But can these products directly modulate immune function and influence inflammatory diseases? Here, Nature Reviews Immunology asks four experts to discuss these issues and provide their thoughts on the future application of probiotics as a disease therapy.

PMID:
23007572
DOI:
10.1038/nri3312
[Indexed for MEDLINE]

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