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J Pediatr Hematol Oncol. 2014 Jan;36(1):e46-8. doi: 10.1097/MPH.0b013e31826e7d9d.

Life-threatening agranulocytosis, anemia, and plasmacytosis after dipyrone use for fever in a child.

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  • 1*Department of Pediatric Hematology †Pediatrics Infectious Diseases Units of the Department of Pediatrics; Medical School of Gazi University, Ankara, Turkey.

Abstract

Dipyrone or metamizole Na (Novalgin) is commonly used as an antipyretic, analgesic, and spasmolytic agent in some parts of the world; however, it is banned in developed countries because of severe side effects. Here we present a case of a 4-year-old boy who developed life-threatening agranulocytosis, anemia, and marked plasmacytosis in his bone marrow after dipyrone use for fever, which resolved with steroid therapy.

PMID:
23007418
DOI:
10.1097/MPH.0b013e31826e7d9d
[PubMed - indexed for MEDLINE]
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