Send to

Choose Destination
Int Ophthalmol. 2013 Feb;33(1):47-52. doi: 10.1007/s10792-012-9628-z. Epub 2012 Sep 22.

Inter-observer agreement for spectral- and time-domain optical coherence tomography image grading: a prospective study.

Author information

Department of Ophthalmology, University Hospital Zurich, Zurich, Switzerland.


The purpose of this study was to compare inter-observer agreement of Stratus™ OCT versus Spectralis™ OCT image grading in patients with neovascular age-related macular degeneration (AMD). Thirty eyes with neovascular AMD were examined with Stratus™ OCT and Spectralis™ OCT. Four different scan protocols were used for imaging. Three observers graded the images for the presence of various pathologies. Inter-observer agreement between OCT models was assessed by calculating intra-class correlation coefficients (ICC). In Stratus™ OCT highest interobserver agreement was found for subretinal fluid (ICC: 0.79), and in Spectralis™ OCT for intraretinal cysts (IRC) (ICC: 0.93). Spectralis™ OCT showed superior interobserver agreement for IRC and epiretinal membranes (ERM) (ICC(Stratus™): for IRC 0.61; for ERM 0.56; ICC(Spectralis™): for IRC 0.93; for ERM 0.84). Increased image resolution of Spectralis™ OCT did improve the inter-observer agreement for grading intraretinal cysts and epiretinal membranes but not for other retinal changes.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Springer Icon for Bern Open Repository and Information System
Loading ...
Support Center