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Exp Cell Res. 2013 Jan 15;319(2):142-6. doi: 10.1016/j.yexcr.2012.09.004. Epub 2012 Sep 19.

Autophagic lysosome reformation.

Author information

1
State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University-Peking University Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

Abstract

Autophagy is an evolutionarily conserved lysosome-dependent degradation pathway. In recent years, many important advances have been made in understanding the cellular and molecular mechanism of autophagosome formation. However, the late stages of autophagy-the cellular events after formation of the autolysosome-are relatively rarely studied. In this review, we discussed the cellular process and molecular mechanism of autophagic lysosome reformation, a cellular events which defines the terminal stage of autophagy.

PMID:
22999865
DOI:
10.1016/j.yexcr.2012.09.004
[Indexed for MEDLINE]

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