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Am J Pathol. 2012 Nov;181(5):1513-7. doi: 10.1016/j.ajpath.2012.09.001. Epub 2012 Sep 20.

NF-κB and hypoxia: a double-edged sword in atherosclerosis.

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1
Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Abstract

This Commentary highlights the article by Fang et al, which describes novel mouse models of chronic intermittent hypoxia (CIH)-induced atherosclerosis, revealing that loss of the NF-κB p50 subunit increased atherosclerosis in the presence of CIH.

PMID:
22999810
PMCID:
PMC3483811
DOI:
10.1016/j.ajpath.2012.09.001
[Indexed for MEDLINE]
Free PMC Article
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