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Nanomedicine (Lond). 2013 Feb;8(2):215-22. doi: 10.2217/nnm.12.96. Epub 2012 Sep 24.

Experimental study of electromagnetic heating of gold nanoparticle dispersions at 200 kHz.

Author information

1
School of Engineering & Materials Science, Queen Mary University of London, London, UK.

Abstract

AIM:

Remote heating of gold nanoparticles (GNPs) by low frequency electromagnetic field has been recently proposed as a potential thermal treatment for deep-seated tumors - almost all the studies were conducted on a commercial device at 13.56 MHz. This work investigates the electromagnetic heating of GNP dispersions at 200 kHz.

METHODS:

GNPs are synthesized based on an improved citrate reduction method, and the influence of particle concentration and impurity on the bulk heating effect at 200 kHz are investigated.

RESULTS & CONCLUSION:

The results demonstrate that GNPs alone can contribute to an appreciable bulk temperature increase, which increases with GNP concentration in a nonlinear fashion. For a nonmagnetic material, the specific absorption rate of GNPs can reach that of Fe(3)O(4) nanoparticle dispersions. Such a result cannot be explained by either the Joule heating or hysteresis heating mechanism.

PMID:
22998408
DOI:
10.2217/nnm.12.96
[Indexed for MEDLINE]
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