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J Occup Environ Med. 2012 Oct;54(10):1300-8. doi: 10.1097/JOM.0b013e31825f30ab.

Development of the Huntington disease work function scale.

Collaborators (320)

Wassink T, Cross S, Kimble M, Ryan P, Wood J, Epping EA, Beglinger LJ, Chiu E, Yastrubetskaya O, Preston J, Goh A, Fonseka C, Antonopoulos S, Loi S, Chua P, Komiti A, Raymond L, Santos RD, Carter K, Decolongon J, Rosenblatt A, Ross CA, Shpritz B, Yoritomo N, Welsh C, Mallonee WM, Suter G, Addison J, Samii A, Macaraeg A, Jones R, Wood-Siverio C, Factor SA, Testa C, Barker RA, Mason S, Goodman A, DiPietro A, McCusker E, Griffith J, Loy C, Gunn D, Landwehrmeyer BG, Orth M, Süβmuth S, Barth K, Trautmann S, Quaid K, Wesson M, Wojcieszek J, Guttman M, Sheinberg A, Karmalkar I, Perlman S, Clemente B, Johnson A, Geschwind MD, Gooblar J, Kang G, Warner T, Burrows M, Novak M, Andrews T, Rosser E, Tabrizi S, Rosser A, Price K, Hunt S, Marshall F, Chesire A, Wodarski M, Hickey C, Suchowersky O, Furtado S, Klimek ML, Panegyres P, Lee J, Andrew S, Perlmutter J, Barton S, Schmidt A, Miedzybrodzka Z, Rae D, D'Alessandro M, Craufurd D, Fullam R, Bek J, Howard E, Mazzoni P, Marder K, Wasserman P, Kumar R, Erickson D, Wheelock V, Tempkin T, Kjer L, Baynes K, Jankovic J, Hunter C, Ondo W, Martin W, King P, Wieler M, Sran S, Ahmed A, Rao S, Reece C, Zimbelman J, Bea A, Newman E, Bura A, Mourany L, Schulz J, Paulsen J, Epping EA, Johnson H, Smith M, Williams J, Beglinger L, Long J, Mills JA, Aylward E, Biglan K, Leavitt B, MacDonald M, Nance M, Erwin C, Leavitt B, Hayden M, DiDonato S, Evans K, Matson W, Peterson A, Tabrizi S, Borowsky B, Juhl A, Mills JA, Wang K, Weir D, Vonsattell JP, Moskowitz C, Leserman A, Schaul L, Vik S, Harrington D, Castillo G, Morison J, Reed J, Diaz M, Dobbins I, Hershey T, Foster E, Moore D, Westervelt H, Davis J, Tremont G, Smith M, Moser DJ, Beglinger LJ, Rowe K, Wenman G, Theriault D, Gehl C, Matheson K, Siedlecki K, VanWalsem M, Bonner S, Elias G, Gover M, Bernier R, Faust M, Borowski B, Carlozzi N, Duff K, Georgiou-Karistianis N, Stout J, Lange H, Papp K, Williams J, Beglinger LJ, Leserman A, Ro E, Clark LA, Downing N, Laing J, Rees K, Harreld M, Vik S, Ready R, Vaccarino A, Farias S, Carlozzi N, Gehl C, MacDonald M, Gusella J, Myers R, Hayden M, Wassink T, Epping EA, Juhl A, Mills J, Wang K, Miedzybrodzka Z, Ross C, Pierson R, Jones K, Marietta J, McDowell W, Harris G, Kim EY, Johnson H, Wassink T, Ashburner J, Potkin S, Toga A, Aylward E, Axelson E, Ross CA, Miller M, Reading S, Beg MF, Magnotta VA, Helmer K, Lim K, Lowe M, Mori S, Song A, Turner J, Rao S, Beall E, Koenig K, Phillips M, Reece C, Zimbelman J, Bryant A, Juhl A, Jones K, Wenman G, Biglan K, Marder K, Corey-Bloom J, Geschwind M, Reilmann R, Unds Z, Juhl A, Epping EA, Downing N, Fiedorowicz J, Robinson R, Smith M, Beglinger L, Mills J, Rees K, Harreld M, Ruggle A, Vik S, Williams J, Liu D, Moser D, Rowe K, Anderson K, Craufurd D, Groves M, Vaccarino A, Evans K, Duijn Ev, Chua P, Quaid K, Long JD, Kim JI, Mills JA, Harrison B, Zhang Y, Liu D, Lu W, Lourens S, Nance M, Leserman A, Doucette N, Kimble M, Ryan P, Thumma K, Waterman E, Hinkel J, Erwin C, Epping EA, Williams J, Doucette N, Leserman A, Mills J, Schaul L, Vik S, Nance M, Hughes L, Johnson H, Connell R, Pease K, Rogers B, Smith J, Wu S, Zschiegner R, Carney E, McKirgan B, Scully M, Wyse R, Bockholt J, Werling-Witkoske C, Ennis G, Vik S, Anderson K, Rapp J, Thompson S, Davis L, Henneberry M, Dudler A, Schumacher J, Stout C, Blanchard S, Montross K, Danz P.

Author information

1
American Board of Internal Medicine, Philadelphia, PA, USA.

Abstract

OBJECTIVE:

A work function measure specific for persons with prodromal Huntington disease (HD) was created to assist with workplace accommodations.

METHODS:

A self-report HD Work Function (HDWF) measure was developed from focus group and expert validation.

RESULTS:

Pilot studies with 238 people with prodromal HD, and 185 companions; and 89 people without prodromal HD, and 70 companions indicate that HDWF has acceptable internal consistency (Cronbach α = 0.77), acceptable interrater reliability (r = 0.58), and acceptable convergent validity with selected items from the Endicott Work Productivity Scale (r = -0.56), Social Adjustment Scale-Self Report (r = -0.29), and Everyday Cognition (r = -0.70). The HDWF can distinguish between people with prodromal HD and people with an HD family history who do not have prodromal HD (P < 0.0001).

CONCLUSIONS:

The HDWF is a brief self-assessment that may be used to monitor work function.

PMID:
22995807
PMCID:
PMC3466392
DOI:
10.1097/JOM.0b013e31825f30ab
[Indexed for MEDLINE]
Free PMC Article
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