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Pediatr Dermatol. 2014 Jan-Feb;31(1):116-7. doi: 10.1111/j.1525-1470.2012.01801.x. Epub 2012 Sep 20.

An adolescent boy with urticaria to water: review of current treatments for aquagenic urticaria.

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Department of Dermatology, Robert Wood Johnson University Hospital, One World's Fair Drive, Suite 2400 Somerset, New Jersey 08873.


We report the case of an adolescent boy with aquagenic urticaria unresponsive to oral antihistamine therapy. We successfully treated his condition by topical application of a petrolatum-containing cream as a protective coating. To our knowledge, this is the first report showing the use of topical therapy alone to treat aquagenic urticaria in a child. Based on the effectiveness, safety profile, and ease of use, clinicians may wish to consider this regimen as a first-line therapy.

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