Format

Send to

Choose Destination
Epidemiol Infect. 2013 Jun;141(6):1267-75. doi: 10.1017/S0950268812002063. Epub 2012 Sep 19.

Identifying the seasonal origins of human campylobacteriosis.

Author information

1
University of Aberdeen, School of Biological Sciences, Cruickshank Building, Aberdeen, UK. n.strachan@abdn.ac.uk

Abstract

Human campylobacteriosis exhibits a distinctive seasonality in temperate regions. This paper aims to identify the origins of this seasonality. Clinical isolates [typed by multi-locus sequence typing (MLST)] and epidemiological data were collected from Scotland. Young rural children were found to have an increased burden of disease in the late spring due to strains of non-chicken origin (e.g. ruminant and wild bird strains from environmental sources). In contrast the adult population had an extended summer peak associated with chicken strains. Travel abroad and UK mainland travel were associated with up to 17% and 18% of cases, respectively. International strains were associated with chicken, had a higher diversity than indigenous strains and a different spectrum of MLST types representative of these countries. Integrating empirical epidemiology and molecular subtyping can successfully elucidate the seasonal components of human campylobacteriosis. The findings will enable public health officials to focus strategies to reduce the disease burden.

PMID:
22989449
PMCID:
PMC4003528
DOI:
10.1017/S0950268812002063
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Cambridge University Press Icon for PubMed Central
Loading ...
Support Center