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Adv Mater. 2012 Jul 24;24(28):3878-86.

Biologically responsive polymeric nanoparticles for drug delivery.

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Division of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, Boston MA 02215, USA.


Responsive nanoparticles that release their drug cargo in accordance with a change in pH or oxidative stress are of significant clinical interest as this approach offers the opportunity to link drug delivery to a specific location or disease state. This research news article reviews the current state of this field by examining a series of published articles that highlight the novelty and benefits of using responsive polymeric particles to achieve functionally-targeted drug delivery.

[Indexed for MEDLINE]

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