[Update of the usefulness of α-blockers in the treatment of different urologic pathologies]

Med Clin (Barc). 2012 Dec 1;139(13):582-7. doi: 10.1016/j.medcli.2012.06.006. Epub 2012 Sep 14.
[Article in Spanish]

Abstract

Objective: To review the role of α-blockers in various urological conditions such as benign prostatic hyperplasia, overactive bladder, chronic prostatitis, and erectile dysfunction and as expulsive treatment of distal ureteral stones.

Material and methods: We reviewed the latest scientific evidence in all the fields mentioned above, performing a critical analysis.

Conclusion: α-blockers are now considered first-line treatment in lower urinary tract symptoms secondary to benign prostatic hyperplasia, but the indications go beyond, and are able to improve, alone or in combination with other drugs, the previously mentioned pathologies. The uroselective properties of some α-blockers make them a highly safe medication.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adrenergic alpha-Antagonists / therapeutic use*
  • Aged
  • Chronic Disease
  • Clinical Trials as Topic
  • Comorbidity
  • Erectile Dysfunction / drug therapy
  • Erectile Dysfunction / epidemiology
  • Erectile Dysfunction / physiopathology
  • Humans
  • Male
  • Middle Aged
  • Multicenter Studies as Topic
  • Muscle, Smooth / drug effects
  • Prostatic Hyperplasia / complications
  • Prostatitis / drug therapy
  • Ureteral Calculi / drug therapy
  • Urinary Bladder / drug effects
  • Urinary Bladder, Overactive / drug therapy
  • Urination Disorders / drug therapy*
  • Urination Disorders / epidemiology
  • Urination Disorders / etiology
  • Urination Disorders / physiopathology

Substances

  • Adrenergic alpha-Antagonists