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Am J Ment Retard. 1990 Jan;94(4):442-7.

Cytogenetic survey for autistic fragile X carriers in a mental retardation center.

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1
University of Florida College of Medicine.

Abstract

A cytogenetic survey of 67 individuals previously identified as having mental retardation and autistic behaviors revealed 1 person (1.5%) with the fragile X chromosome (fra[X]) and 3 (4.5%) with autosome abnormalities. This low prevalence of fra(X) indicates that most persons with fra(X) in this mental retardation center did not have autistic behaviors severe enough to be identified as a secondary psychiatric diagnosis. The presence of other chromosomal abnormalities is consistent with the known causal heterogeneity of autism in mental retardation populations.

PMID:
2297426
[Indexed for MEDLINE]
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