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J Obstet Gynaecol Can. 2012 Sep;34(9):830-835. doi: 10.1016/S1701-2163(16)35381-6.

Ten-year, thirty-year, and lifetime cardiovascular disease risk estimates following a pregnancy complicated by preeclampsia.

Author information

1
Department of Obstetrics & Gynaecology, Kingston General Hospital, Queen's University, Kingston ON; Department of Biomedical and Molecular Sciences, Kingston General Hospital, Queen's University, Kingston ON.
2
Department of Obstetrics and Gynecology, Ottawa Health Research Institute, University of Ottawa, Ottawa ON.

Abstract

OBJECTIVE:

To calculate the cardiovascular disease (CVD) risk estimates for women following a pregnancy with or without preeclampsia.

METHODS:

We calculated 10-year, 30-year, and lifetime CVD risk estimates at one year postpartum for women recruited into the Pre-Eclampsia New Emerging Team's prospective cohort.

RESULTS:

Complete CVD risk screening data were obtained from 118 control women and 99 preeclamptic women. A total of 18.2% of preeclamptic women and 1.7% of control women had a high 10-year risk (OR 13.08; 95% CI 3.38 to 85.5), 31.3% of preeclamptic women and 5.1% of control women had a high 30-year risk (OR 8.43; 95% CI 3.48 to 23.23), and 41.4% of preeclamptic women and 17.8% of control women had a high lifetime risk for CVD (OR 3.25; 95% CI 1.76 to 6.11).

CONCLUSIONS:

The association of preeclampsia with the future development of CVD makes pregnancy an early window of opportunity for the preservation of health and prevention of CVD.

PMID:
22971451
DOI:
10.1016/S1701-2163(16)35381-6
[Indexed for MEDLINE]

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