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Oxid Med Cell Longev. 2012;2012:491759. doi: 10.1155/2012/491759. Epub 2012 Aug 30.

Apple can act as anti-aging on yeast cells.

Author information

1
Dipartimento di Biologia e Biotecnologie Charles Darwin, Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Roma, Italy.

Abstract

In recent years, epidemiological and biochemical studies have shown that eating apples is associated with reduction of occurrence of cancer, degenerative, and cardiovascular diseases. This association is often attributed to the presence of antioxidants such as ascorbic acid (vitamin C) and polyphenols. The substances that hinder the presence of free radicals are also able to protect cells from aging. In our laboratory we used yeast, a unicellular eukaryotic organism, to determine in vivo efficacy of entire apples and their components, such as flesh, skin and polyphenolic fraction, to influence aging and oxidative stress. Our results indicate that all the apple components increase lifespan, with the best result given by the whole fruit, indicating a cooperative role of all apple components.

PMID:
22970337
PMCID:
PMC3437301
DOI:
10.1155/2012/491759
[Indexed for MEDLINE]
Free PMC Article

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