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Am J Ind Med. 2012 Nov;55(11):991-9. doi: 10.1002/ajim.22113. Epub 2012 Sep 11.

Occupational exposures and mortality from cardiovascular disease among women textile workers in Shanghai, China.

Author information

1
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195-7234, USA. lgallag@u.washington.edu

Abstract

BACKGROUND:

Exposure to textile fiber dusts, like particulate air pollution, may be associated with cardiovascular disease (CVD) mortality. Bacterial endotoxin, a potent inflammagen found in cotton dust, may be a specific risk factor.

METHODS:

Female textile workers (N = 267,400) in Shanghai, China were followed for CVD mortality (1989-2000). Factory exposures were approximated by sector classifications based on materials and processes. Quantitative endotoxin and cotton dust measures were available for a subcohort (n = 3,188). Cox proportional hazards modeling was used to estimate hazard ratios (HR) and 95% confidence interval (CI).

RESULTS:

Slightly elevated mortality risk for the cotton sector was seen for ischemic stroke (HR = 1.12, 95% CI: 0.97-1.31) and hemorrhagic stroke (HR = 1.12, 95% CI: 1.02-1.23). Similar hemorrhagic stroke mortality risk was observed in high dust sectors (HR = 1.12, 95% CI: 1.02-1.24). No association was observed for ischemic heart disease.

CONCLUSIONS:

Exposures in textile factories may have contributed to CVD mortality among this cohort. The specific components of these exposures that may be harmful are not clear and should be further investigated.

PMID:
22968969
PMCID:
PMC3515077
DOI:
10.1002/ajim.22113
[Indexed for MEDLINE]
Free PMC Article
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