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Cell Stem Cell. 2012 Sep 7;11(3):291-301. doi: 10.1016/j.stem.2012.08.010.

Stem cells in the face: tooth regeneration and beyond.

Author information

1
Center for Craniofacial Regeneration, Columbia University Medical Center, 630 West 168 Street - PH7E, New York, NY 10032, USA. jmao@columbia.edu

Erratum in

  • Cell Stem Cell. 2012 Oct 5;11(4):579. Robey, Pamela G [removed].

Abstract

The face distinguishes one person from another. Postnatal orofacial tissues harbor rare cells that exhibit stem cell properties. Despite unmet clinical needs for reconstruction of tissues lost in congenital anomalies, infections, trauma, or tumor resection, how orofacial stem/progenitor cells contribute to tissue development, pathogenesis, and regeneration is largely obscure. This perspective article critically analyzes the current status of our understanding of orofacial stem/progenitor cells, identifies gaps in our knowledge, and highlights pathways for the development of regenerative therapies.

PMID:
22958928
PMCID:
PMC4093804
DOI:
10.1016/j.stem.2012.08.010
[Indexed for MEDLINE]
Free PMC Article

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