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Org Lett. 2012 Sep 21;14(18):4830-3. Epub 2012 Sep 6.

Synthesis of pyrrolo[2,3-b]indole via iodine(III)-mediated intramolecular annulation.

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1
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.

Abstract

New synthetic procedures for the pyrrolo[2,3-b]indole skeleton have been developed via intramolecular annulation of indole derivatives under iodine(III). A series of indole derivatives with different protecting groups or substitutions were explored to facilitate the corresponding pyrrolo[2,3-b]indole compounds in excellent yields.

PMID:
22953796
DOI:
10.1021/ol302158h
[Indexed for MEDLINE]
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