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Nat Cell Biol. 2012 Sep;14(9):900-1. doi: 10.1038/ncb2571.

Visualizing global effects of the DNA damage response.

Author information

1
MRC National Institute for Medical Research, Division of Stem Cell Biology and Developmental Genetics, Mill Hill, London NW7 1AA, UK. pthorpe@nimr.mrc.ac.uk

Abstract

In a large-scale analysis, the effects of DNA damage on the levels and localization of almost every protein in an organism have now been tracked in living cells. It is shown that that although many proteins change their position or concentration, they rarely do both.

PMID:
22945255
DOI:
10.1038/ncb2571
[Indexed for MEDLINE]

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