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Neonatology. 2012;101(4):353-9. doi: 10.1159/000337356. Epub 2012 Jun 1.

Current technology in the diagnosis of developmentally related lung disorders.

Author information

1
Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo 63110, USA.

Abstract

Respiratory disorders that present in the newborn period may result from structural, functional, or acquired mechanisms that limit gas exchange between the airspace and vascular bed. Exciting new imaging, gene sequencing, mass spectrometry, and molecular and cell-based techniques are enhancing our understanding of mechanisms of disease; highlighting the complexity of interactions between genes, development, and environment in the manifestation of health and disease; and becoming part of the clinical armamentarium for the care of patients. Some of these technologies and their clinical potential are briefly reviewed in this paper.

PMID:
22940625
PMCID:
PMC3568753
DOI:
10.1159/000337356
[Indexed for MEDLINE]
Free PMC Article

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