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Nat Methods. 2012 Sep;9(9):889-95. doi: 10.1038/nmeth.2114. Epub 2012 Aug 30.

Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy.

Author information

1
Electrical Engineering Department, University of California, Los Angeles, Los Angeles, California, USA.

Abstract

We discuss unique features of lens-free computational imaging tools and report some of their emerging results for wide-field on-chip microscopy, such as the achievement of a numerical aperture (NA) of ∼0.8-0.9 across a field of view (FOV) of more than 20 mm(2) or an NA of ∼0.1 across a FOV of ∼18 cm(2), which corresponds to an image with more than 1.5 gigapixels. We also discuss the current challenges that these computational on-chip microscopes face, shedding light on their future directions and applications.

PMID:
22936170
PMCID:
PMC3477589
DOI:
10.1038/nmeth.2114
[Indexed for MEDLINE]
Free PMC Article

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