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Acta Biochim Biophys Sin (Shanghai). 2012 Nov;44(11):897-901. doi: 10.1093/abbs/gms067. Epub 2012 Aug 30.

Post-translational regulation of FOXO.

Author information

1
State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

Abstract

The Forkhead box O (FOXO) family transcription factors play critical roles in a series of cellular processes, including the cell cycle, cell death, metabolism, and oxidative stress resistance. FOXO proteins are subject to several post-translational modifications, which are closely related to their activity. In this paper, we review the post-translational modifications of FOXOs and their biological functions.

PMID:
22935512
DOI:
10.1093/abbs/gms067
[Indexed for MEDLINE]

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