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Zhonghua Nan Ke Xue. 2012 Aug;18(8):764-7.

[Shengjing prescription improves semen parameters of oligoasthenozoospermia patients: efficacy and mechanism].

[Article in Chinese]

Author information

1
Center of Reproduction and Heredity, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250011, China.

Abstract

OBJECTIVE:

To investigate the clinical efficacy of Shengjing prescription for oligoasthenozoospermia and its action mechanism.

METHODS:

We equally assigned 120 patients with oligoasthenozoospermia to receive Shengjing prescription (treatment group) and vitamin E (control group), respectively, for 12 weeks. Before and after the treatment, were obtained sperm concentration, sperm motility, the percentage of morphologically normal sperm, the levels of serum follicle-stimulating hormone (FSH), testosterone (T) and luteinizing hormone (LH), sperm DNA fragmentation index (DFI), the percentage of hypotonic swelling sperm, and the levels of seminal plasma elastase, x-glucosidase, fructose, zinc and acrosin.

RESULTS:

Compared with vitamin E, Shengling prescription significantly improved sperm concentration, motility and morphology (P < 0.01), decreased the serum FSH level, elevated the serum T level (P <0. 01) , reduced DFI and seminal plasma elastase, and increased the percentage of hypotonic swelling sperm as well as the levels of seminal plasma cx-glucosidase, fructose, zinc and acrosin.

CONCLUSION:

Shengjing prescription improves semen parameters of patients with oligoasthenozoospermia at multiple levels and through multiple channels.

PMID:
22934526
[Indexed for MEDLINE]

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