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Zhonghua Nan Ke Xue. 2012 Aug;18(8):764-7.

[Shengjing prescription improves semen parameters of oligoasthenozoospermia patients: efficacy and mechanism].

[Article in Chinese]

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Center of Reproduction and Heredity, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250011, China.



To investigate the clinical efficacy of Shengjing prescription for oligoasthenozoospermia and its action mechanism.


We equally assigned 120 patients with oligoasthenozoospermia to receive Shengjing prescription (treatment group) and vitamin E (control group), respectively, for 12 weeks. Before and after the treatment, were obtained sperm concentration, sperm motility, the percentage of morphologically normal sperm, the levels of serum follicle-stimulating hormone (FSH), testosterone (T) and luteinizing hormone (LH), sperm DNA fragmentation index (DFI), the percentage of hypotonic swelling sperm, and the levels of seminal plasma elastase, x-glucosidase, fructose, zinc and acrosin.


Compared with vitamin E, Shengling prescription significantly improved sperm concentration, motility and morphology (P < 0.01), decreased the serum FSH level, elevated the serum T level (P <0. 01) , reduced DFI and seminal plasma elastase, and increased the percentage of hypotonic swelling sperm as well as the levels of seminal plasma cx-glucosidase, fructose, zinc and acrosin.


Shengjing prescription improves semen parameters of patients with oligoasthenozoospermia at multiple levels and through multiple channels.

[Indexed for MEDLINE]

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