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Rev Med Suisse. 2012 Jul 11;8(348):1458-63.

[Effects of calcium and vitamin D supplementations on cardiovascular disease: review article].

[Article in French]

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Unité d'épidémiologie populationnelle, Département de médecine communautaire, de premier recours et des urgences, HUG, 1211 Genève 14.


Studies exploring the effect of calcium supplementation on cardiovascular risk suggest that systolic blood pressure decreases with supplementation. A lower calcium intake has been associated with an increased risk of stroke. By contrast, calcium supplementation may increase the risk of myocardial infarction. The effect of vitamin D supplementation on blood pressure is still unclear and no effect of vitamin D supplementation on coronary heart disease or stroke has been clearly demonstrated. There is a lack of randomized clinical trials primarily addressing the effect of these parameters on CVD. Currently, the use of calcium and vitamin D supplementations for the prevention of cardiovascular disease is not justified.

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