Format

Send to

Choose Destination
See comment in PubMed Commons below
Autism Res Treat. 2012;2012:242537. doi: 10.1155/2012/242537. Epub 2012 May 31.

Assessment and treatment in autism spectrum disorders: a focus on genetics and psychiatry.

Author information

1
Department of Psychiatry and Behavioral Sciences, Kansas University Medical Center, 3901 Rainbow Blvd., MS4015, Kansas City, KS 66160, USA.

Abstract

Autism spectrum disorders (ASDs) are neurobehavioral disorders characterized by abnormalities in three behavioral domains including social interaction, impaired communication, and repetitive stereotypic behaviors. ASD affects approximately 1% of children and is on the rise with significant genetic mechanisms underlying these disorders. We review the current understanding of the role of genetic and metabolic factors contributing to ASD with the use of new genetic technology. Fifty percent is diagnosed with chromosomal abnormalities, small DNA deletions/duplications, single-gene conditions, or metabolic disturbances. Genetic evaluation is discussed along with psychiatric treatment and approaches for selection of medication to treat associated challenging behaviors or comorbidities seen in ASD. We emphasize the importance of prioritizing treatment based on target symptom clusters and in what order for individuals with ASD, as the treatment may vary from patient to patient.

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Hindawi Publishing Corporation Icon for PubMed Central
    Loading ...
    Support Center