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Am J Perinatol. 2013 Mar;30(3):185-90. doi: 10.1055/s-0032-1322517. Epub 2012 Aug 28.

The impact of tobacco use on preterm premature rupture of the membranes.

Author information

1
Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA. Robert.Andres@imail.org

Abstract

OBJECTIVE:

To determine if tobacco use increases the incidence of preterm premature rupture of the membranes (pPROM) or alters perinatal outcomes after pPROM.

STUDY DESIGN:

This is a secondary analysis of the databases of three completed Eunice Kennedy Shriver National Institute of Child Health and Human Development-supported Maternal Fetal Medicine Units Network studies. Self-reported tobacco exposure data was obtained. Its relationship with the incidence of pPROM and associated neonatal outcome measures were assessed.

RESULTS:

There was no difference in the incidence of pPROM when comparing nonsmokers to those using tobacco. Although a trend was seen between the incidence of pPROM and the amount smoked, this did not reach statistical significance. Among the patients with pPROM, the use of tobacco was not associated with an increase in perinatal morbidity.

CONCLUSION:

Our data do not support a significant relationship between tobacco use and pPROM.

PMID:
22930157
PMCID:
PMC3962832
DOI:
10.1055/s-0032-1322517
[Indexed for MEDLINE]
Free PMC Article

Publication type, MeSH terms, Supplementary concept, Grant support

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