Format

Send to

Choose Destination
Clin Chest Med. 2012 Sep;33(3):459-71. doi: 10.1016/j.ccm.2012.06.007. Epub 2012 Jul 25.

Biomarkers in asthma: a real hope to better manage asthma.

Author information

1
Department of Pathobiology, Lerner Research Institute, Cleveland Clinic Lerner College of Medicine-CWRU, 9500 Euclid Avenue, NC22, Cleveland, OH 44195-0001, USA. erzurus@ccf.org

Abstract

Diagnosis and treatment of asthma are currently based on assessment of patient symptoms and physiologic tests of airway reactivity. Research over the past decade has identified an array of biochemical and cellular biomarkers, which reflect the heterogeneous and multiple mechanistic pathways that may lead to asthma. These mechanistic biomarkers offer hope for optimal design of therapies targeting the specific pathways that lead to inflammation. This article provides an overview of blood, urine, and airway biomarkers; summarizes the pathologic pathways that they signify; and begins to describe the utility of biomarkers in the future care of patients with asthma.

PMID:
22929095
PMCID:
PMC3494969
DOI:
10.1016/j.ccm.2012.06.007
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center