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J Asian Nat Prod Res. 2012;14(9):856-61. doi: 10.1080/10286020.2012.700925. Epub 2012 Aug 28.

Two new triterpene saponins from Gynostemma pentaphyllum.

Author information

1
College of Food Science, Shenyang Agriculture University, Shenyang, China.

Abstract

Two new dammarane-type triterpene saponins, gypenbiosides A (1) and B (2), were isolated from the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino. Their structural elucidations were accomplished mainly on the basis of the interrelation of spectroscopic methods, such as IR, HR-TOF-MS, and NMR. The cytotoxic activity was evaluated against one human cancer cell line HL-60 using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.

PMID:
22924674
DOI:
10.1080/10286020.2012.700925
[Indexed for MEDLINE]

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