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Adv Skin Wound Care. 2012 Sep;25(9):420-8.

Sickle cell disease and leg ulcers.

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1
Duke University Medical Center, Durham, North Carolina, USA.

Abstract

Sickle cell disease is a genetic disorder of hemoglobin synthesis leading to a deformation of the red blood cell. This disorder is associated with painful, slow-to-heal leg ulcers. This article discusses the wound bed preparation paradigm as a guide to the treatment of sickle cell-associated leg ulcers.

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