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Acta Psychiatr Scand. 2013 Mar;127(3):210-6. doi: 10.1111/acps.12000. Epub 2012 Aug 20.

Clinical and sociodemographic comparison of people at high-risk for psychosis and with first-episode psychosis.

Author information

1
Cameo Early Intervention Services, Cambridgeshire and Peterborough NHS Foundation Trust, UK.

Abstract

OBJECTIVE:

To compare clinical and sociodemographic characteristics previously associated with psychosis, between individuals at high-risk for psychosis (HR) and patients experiencing a first episode psychosis (FEP), to achieve a better understanding of factors associated with psychosis.

METHOD:

Cross-sectional comparison of 30 individuals at HR with 30 age-gender matched FEP, presenting to an early intervention service for psychosis. Participants were followed-up for 2 years to establish the proportion of HR who made the transition into FEP.

RESULTS:

Both groups showed similar socio-clinical characteristics, including immigration status, employment history, marital status, family history of psychotic illness, self-harm and alcohol and drug use. The HR group had a lower level of education, higher burden of trauma, earlier onset of psychiatric symptoms and a longer delay in accessing specialised services. A younger onset of symptoms was associated with a longer delay in accessing services in both groups. After a 2 year follow-up, only three (10%) of the HR group made a transition into FEP.

CONCLUSION:

The similarities observed between individuals at HR and those with FEP suggest that known variables associated with psychosis may be equally prevalent in people at HR who do not develop a psychotic disorder.

PMID:
22906094
DOI:
10.1111/acps.12000
[Indexed for MEDLINE]

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