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Cell. 2012 Aug 17;150(4):671-2. doi: 10.1016/j.cell.2012.07.026.

Poxvirus use a "gene accordion" to tune out host defenses.

Author information

1
Department of Microbiology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA. jrroth@ucdavis.edu

Abstract

A multistep process of gene amplification, mutation, and reduction allows poxvirus to overcome host antiviral defenses. The mechanism speeds genetic adaptation and promises to be broadly applicable in many biological settings.

PMID:
22901801
DOI:
10.1016/j.cell.2012.07.026
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