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Cardiovasc Ultrasound. 2012 Aug 17;10:35. doi: 10.1186/1476-7120-10-35.

A modified regimen of extracorporeal cardiac shock wave therapy for treatment of coronary artery disease.

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  • 1Department of Cardiology, 1st Hospital of Kunming Medical University, Kunming, Yunnan, PRC.

Abstract

BACKGROUND:

Cardiac shock wave therapy (CSWT) improves cardiac function in patients with severe coronary artery disease (CAD). We aimed to evaluate the clinical outcomes of a new CSWT treatment regimen.

METHODS:

The 55 patients with severe CAD were randomly divided into 3 treatment groups. The control group (n = 14) received only medical therapy. In group A ( n = 20), CSWT was performed 3 times within 3 months. In group B ( n = 21), patients underwent 3 CSWT sessions/week, and 9 treatment sessions were completed within 1 month. Primary outcome measurement was 6-minute walk test (6MWT). Other measurements were also evaluated.

RESULTS:

The 6MWT, CCS grading of angina, dosage of nitroglycerin, NYHA classification, and SAQ scores were improved in group A and B compared to control group.

CONCLUSIONS:

A CSWT protocol with 1 month treatment duration showed similar therapeutic efficacy compared to a protocol of 3 months duration.

CLINICAL TRIAL REGISTRY:

We have registered on ClinicalTrials.gov, the protocol ID is CSWT IN CHINA.

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