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Gut Microbes. 2012 Sep-Oct;3(5):468-73. Epub 2012 Aug 15.

Subspecies diversity in bacteriocin production by intestinal Lactobacillus salivarius strains.

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1
Teagasc Food Research Centre, Cork, Ireland.

Abstract

A recent comparative genomic hybridization study in our laboratory revealed considerable plasticity within the bacteriocin locus of gastrointestinal strains of Lactobacillus salivarius. Most notably, these analyses led to the identification of two novel unmodified bacteriocins, salivaricin L and salivaricin T, produced by the neonatal isolate L. salivarius DPC6488 with immunity, regulatory and export systems analogous to those of abp118, a two-component bacteriocin produced by the well characterized reference strain L. salivarius UCC118. In this addendum we discuss the intraspecific diversity of our seven bacteriocin-producing L. salivarius isolates on a genome-wide level, and more specifically, with respect to their salivaricin loci.

PMID:
22892690
PMCID:
PMC3466502
DOI:
10.4161/gmic.21417
[Indexed for MEDLINE]
Free PMC Article
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