Format

Send to

Choose Destination
See comment in PubMed Commons below
Transcription. 2012 Nov-Dec;3(6):273-6. doi: 10.4161/trns.21525. Epub 2012 Aug 14.

Elongator: transcriptional or translational regulator?

Author information

1
European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.

Abstract

The conserved multi-subunit Elongator complex was initially described as a RNA polymerase II (RNAPII) associated transcription elongation factor, but since has been shown to be involved a variety of different cellular activities. Here, we summarize recent developments in the field and discuss the resulting implications for the proposed multi-functionality of Elongator.

KEYWORDS:

Elongator; tRNA modification; transcription elongation

PMID:
22889844
PMCID:
PMC3630180
DOI:
10.4161/trns.21525
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis Icon for PubMed Central
    Loading ...
    Support Center