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Neuropsychiatr Dis Treat. 2012;8:323-8. doi: 10.2147/NDT.S33259. Epub 2012 Jul 19.

5-HTP efficacy and contraindications.

Author information

1
Clinical Research, NeuroResearch Clinics, Inc, Cape Coral.

Abstract

L-5-hydroxytryptophan (5-HTP) is the immediate precursor of serotonin. It is readily synthesized into serotonin without biochemical feedback. This nutrient has a large and strong following who advocate exaggerated and inaccurate claims relating to its effectiveness in the treatment of depression and a number of other serotonin-related diseases. These assertions are not supported by the science. Under close examination, 5-HTP may be contraindicated for depression in some of the very patients for whom promoters of 5-HTP advocate its use.

KEYWORDS:

5-HTP; 5-hydroxytryptophan; L-5-HTP; L-5-hydroxytryptophan

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