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Macromol Rapid Commun. 2012 Sep 14;33(17):1420-31. doi: 10.1002/marc.201200382. Epub 2012 Aug 7.

Polymeric biomaterials for stem cell bioengineering.

Author information

1
Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials, Hohe Stra├če 6, 01069 Dresden, Germany.

Abstract

This review covers the application of polymeric materials in stem cell bioengineering. Main emphasis is directed towards current material design concepts that mimic distinct exogenous signals of the stem cell microenvironment. Progress within the field of stem cell-specific biomaterials will be discussed, focusing on pluripotent, hematopoietic, mesenchymal and neural stem cells. The future role of biomaterials will be outlined with possible applications for cell reprogramming and engineering cancer cell microenvironments.

PMID:
22887752
DOI:
10.1002/marc.201200382
[Indexed for MEDLINE]

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