Format

Send to

Choose Destination
See comment in PubMed Commons below
Genetics. 2012 Aug;191(4):1073-105. doi: 10.1534/genetics.111.137851.

Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.

Author information

1
Department of Microbiology and Infectiology, RNA-Group, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.

Abstract

The mechanisms that maintain the stability of chromosome ends have broad impact on genome integrity in all eukaryotes. Budding yeast is a premier organism for telomere studies. Many fundamental concepts of telomere and telomerase function were first established in yeast and then extended to other organisms. We present a comprehensive review of yeast telomere biology that covers capping, replication, recombination, and transcription. We think of it as yeast telomeres--soup to nuts.

PMID:
22879408
PMCID:
PMC3415994
DOI:
10.1534/genetics.111.137851
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center