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J Neurosci Rural Pract. 2012 May;3(2):174-7. doi: 10.4103/0976-3147.98224.

Pediatric multifocal glioblastoma multiforme with fulminant course.

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  • 1Department of Neurosurgery, Dr. Achanta Lakshmipathi Neurosurgical Centre, Post Graduate Institute of Neurological Surgery, V.H.S Hospital, Taramani, Chennai, Tamil Nadu, India.


Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor. GBM in children is less common than in adults and has a better prognosis. Pediatric GBM is a rare entity, and a multifocal development in a pediatric GBM is much rarer. We report to you one such rare case of pediatric multifocal GBM in a 5-year-old child who developed rapidly increasing multiple lesions after radiotherapy. More studies are required to study the genetic analysis, tumor behavior, management and outcome of these rare tumors.


Multifocal GBM; multicentric GBM; pediatric GBM; recraniotomy

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